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Presentation synopsis:

What HIV observational cohorts have brought to the field

In the early years of the epidemic, traditional cohorts have established the risk factors for acquiring HIV and helped understanding the natural course of the disease. Nowadays, the most important contributions of cohorts are to document the real-life experiences with the highly effective antiretroviral therapies, their success as well as late-onset or rare adverse events. For the latter, HIV cohorts around the globe have collaborated in an unprecedented manner. As life expectancy of HIV-positive people has increased enormously, many cohorts have expanded their research foci to include aspects of multi-morbidity and polypharmacy.

Speaker biography:

Born in St. Gallen, Switzerland, Bruno Ledergerber finished his Masters‘ degree in Electronic Engineering followed by a PhD on pharmacodynamics of antibiotics at the Swiss Federal Institute of Technology in Zürich. He was head of the Coordination and Data Center of the newly established Swiss HIV Cohort Study from 1988-1995 and is currently Professor at the medical faculty of the University of Zurich, specialised in Clinical Epidemiology and Medical Informatics.

Besides the Scientific Board of the Swiss HIV Cohort Study, he was member of many steering bodies of international collaborations such as EuroSIDA, ART-CC, COHERE and EuroCOORD. Together with colleagues, Bruno Ledergerber has authored or co-authored more than 250 peer-reviewed articles predominantly in the field of HIV cohort studies and was instrumental in setting up the globally accepted HIV Cohorts Data Exchange Protocol (HICDEP) for HIV cohort collaborations.


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